Surface modification of stereoregular and stereocomplex poly(methyl methacrylate) films with biologically identified peptides

Takaaki Date, Satomi Yoshino, Hisao Matsuno, Takeshi Serizawa

    Research output: Contribution to journalArticlepeer-review

    8 Citations (Scopus)

    Abstract

    A study was conducted to demonstrate surface modification of stereoregular and stereocomplex poly(methyl methacrylate) (PMMA) films with biologically identified material-binding peptides (MBP). Isotactic (it)- and syndiotactic (st)-PMMA film surfaces were modified with biotinylated peptides that specifically bound to the polymers and analyzed the binding of streptavidin (SAv) to these immobilized peptides. PMMA stereocomplex (SC) films, which were composed of it- and st-PMMAs, were evaluated by their specific peptides under the same conditions and the results were compared against those of it- and st-PMMAs. The static contact angle of PMMA films on gold-coated glass slides was measured with a commercial apparatus. The surface topology of the PMMA films was visualized by non-contact mode atomic force microscopy (AFM) in air using a silicon cantilever.

    Original languageEnglish
    Pages (from-to)366-369
    Number of pages4
    JournalPolymer Journal
    Volume44
    Issue number4
    DOIs
    Publication statusPublished - Apr 2012

    All Science Journal Classification (ASJC) codes

    • Polymers and Plastics
    • Materials Chemistry

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