Surface potential generation by helical peptide monolayers and multilayers on gold surface

Yukio Imanishi, Yoshiko Miura, Mitsumasa Iwamoto, Shunsaku Kimura, Junzo Umemura

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

Self-assembled monolayers (SAMs) and multilayers of helical peptides were prepared and the surface potentials of the peptide layers were measured to evaluate the contribution of the dipole moment of helical peptides to the surface potential. All the peptides have 2-aminoisobutyric acid (Aib), and adopt helical conformation in the peptide layers. The peptides were immobilized on gold surface by Au+-S- bond or hydrogen bonds to take a vertical orientation to the surface. When the helical peptides were connected to gold surface through the N terminal, the surface potentials were negative. On the other hand, the helical peptide layers exhibited positive surface potentials, when the peptides were connected through the C terminal. These results indicate that the dipole moment of helical peptide is the major factor for generation of the surface potential. The generation of surface potential by the helical peptides was also discussed in terms of a theoretical point of view.

Original languageEnglish
Pages (from-to)287-290
Number of pages4
JournalProceedings of the Japan Academy Series B: Physical and Biological Sciences
Volume75
Issue number10
DOIs
Publication statusPublished - Dec 1999
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Agricultural and Biological Sciences(all)
  • Physics and Astronomy(all)

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