Surgical outcomes of newly categorized peripheral t3 non-small cell lung cancers: Comparisons between chest wall invasion and large tumors (>7 cm)

Makoto Suzuki, Shigetoshi Yoshida, Yasumitsu Moriya, Hidehisa Hoshino, Teruaki Mizobuchi, Tatsuro Okamoto, Ichiro Yoshino

Research output: Contribution to journalArticle

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Abstract

The prognosis for non-small cell lung cancer (NSCLC) with chest wall invasion can vary due to the heterogeneous nature of the cell population. Because NSCLC with large tumors (>7 cm) have been reclassified as T3, the applicability of the new designation must be evaluated. We reviewed 140 patients with chest wall T3 and 28 patients with T3 NSCLC with large tumors, but no chest wall invasion who underwent resection at our institution. Among chest wall T3 patients, elderly T3 patients (G80 years old) who died within 42 months, patients with either lymph node or pulmonary metastasis, or patients with a large tumor (>7 cm) had poorer prognoses than those who had not. The survival rates for cases with chest wall T3 and cases with a large tumor without chest wall invasion were not significantly different. NSCLC patients with chest wall T3 with lymph node, or pulmonary metastasis, or with a large tumor should be considered for further multimodal treatment with or without resection to enhance their survival time. Elderly patients with chest wall invasion may not be good candidates for resection. A large tumor is so aggressive that re-classification of large tumor cases as T3 is suitable.

Original languageEnglish
Pages (from-to)420-424
Number of pages5
JournalInteractive cardiovascular and thoracic surgery
Volume11
Issue number4
DOIs
Publication statusPublished - Oct 1 2010

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Thoracic Wall
Non-Small Cell Lung Carcinoma
Neoplasms
Lymph Nodes
Neoplasm Metastasis
Combined Modality Therapy
Lung
Survival Rate
Survival
Population

All Science Journal Classification (ASJC) codes

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

Cite this

Surgical outcomes of newly categorized peripheral t3 non-small cell lung cancers : Comparisons between chest wall invasion and large tumors (>7 cm). / Suzuki, Makoto; Yoshida, Shigetoshi; Moriya, Yasumitsu; Hoshino, Hidehisa; Mizobuchi, Teruaki; Okamoto, Tatsuro; Yoshino, Ichiro.

In: Interactive cardiovascular and thoracic surgery, Vol. 11, No. 4, 01.10.2010, p. 420-424.

Research output: Contribution to journalArticle

Suzuki, Makoto ; Yoshida, Shigetoshi ; Moriya, Yasumitsu ; Hoshino, Hidehisa ; Mizobuchi, Teruaki ; Okamoto, Tatsuro ; Yoshino, Ichiro. / Surgical outcomes of newly categorized peripheral t3 non-small cell lung cancers : Comparisons between chest wall invasion and large tumors (>7 cm). In: Interactive cardiovascular and thoracic surgery. 2010 ; Vol. 11, No. 4. pp. 420-424.
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