Surgical treatment of intrahepatic cholangiocarcinoma in the USA

Nir Lubezky, Marcelo Facciuto, Norifumi Harimoto, Myron E. Schwartz, Sander S. Florman

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Cholangiocarcinoma (CC) is a malignancy that arises from the epithelial cells of the biliary system (ductules as well as large ducts, and likely from progenitor cells, as well). Intrahepatic CC (ICC) is the second most common primary hepatic malignancy after hepatocellular carcinoma (HCC), and accounts for 10-15% of primary liver cancers. ICC differs from both extrahepatic and CC and HCC and has unique risk factors, histological features, genetic alterations and clinical outcomes. The natural history and results of surgical intervention are not well described as ICC is a relatively uncommon tumor, especially in the USA. This article reviews the literature relevant to the surgical management and outcome of patients with ICC in the USA.

Original languageEnglish
Pages (from-to)124-130
Number of pages7
JournalJournal of Hepato-Biliary-Pancreatic Sciences
Volume22
Issue number2
DOIs
Publication statusPublished - Feb 1 2015

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Cholangiocarcinoma
Hepatocellular Carcinoma
Neoplasms
Biliary Tract
Liver Neoplasms
Natural History
Stem Cells
Therapeutics
Epithelial Cells
Liver

All Science Journal Classification (ASJC) codes

  • Surgery
  • Hepatology

Cite this

Lubezky, N., Facciuto, M., Harimoto, N., Schwartz, M. E., & Florman, S. S. (2015). Surgical treatment of intrahepatic cholangiocarcinoma in the USA. Journal of Hepato-Biliary-Pancreatic Sciences, 22(2), 124-130. https://doi.org/10.1002/jhbp.157

Surgical treatment of intrahepatic cholangiocarcinoma in the USA. / Lubezky, Nir; Facciuto, Marcelo; Harimoto, Norifumi; Schwartz, Myron E.; Florman, Sander S.

In: Journal of Hepato-Biliary-Pancreatic Sciences, Vol. 22, No. 2, 01.02.2015, p. 124-130.

Research output: Contribution to journalArticle

Lubezky, N, Facciuto, M, Harimoto, N, Schwartz, ME & Florman, SS 2015, 'Surgical treatment of intrahepatic cholangiocarcinoma in the USA', Journal of Hepato-Biliary-Pancreatic Sciences, vol. 22, no. 2, pp. 124-130. https://doi.org/10.1002/jhbp.157
Lubezky, Nir ; Facciuto, Marcelo ; Harimoto, Norifumi ; Schwartz, Myron E. ; Florman, Sander S. / Surgical treatment of intrahepatic cholangiocarcinoma in the USA. In: Journal of Hepato-Biliary-Pancreatic Sciences. 2015 ; Vol. 22, No. 2. pp. 124-130.
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