[Susceptible and resistant factors in neuro-immune disease].

Shinya Sato, Jun ichi Kira

Research output: Contribution to journalReview articlepeer-review

Abstract

Neuro-immune diseases (NIDs) are caused by a complex interaction between multiple genetic and environmental factors, both of which can have some impacts on susceptibility or resistance to each disease. Remarkable advance in genome technology made possible the effective screening of thousands of single nucleotide polymorphisms in thousands of samples. Additionally, epidemiological science, supported by microbiology, immunology and biochemistry, has revealed many possible environmental factors. Integrating genetic and environmental research data will pave the way to inform and personalize therapeutic decision-making in NIDs. This review aims to discuss susceptible and resistant factors that have attracted the most attention in the recent years, especially focusing on multiple sclerosis, which is one of the most common NIDs.

Original languageEnglish
Pages (from-to)783-788
Number of pages6
JournalUnknown Journal
Volume71
Issue number5
Publication statusPublished - May 2013

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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