Suzuki coupling for protein modification

Akio Ojida; Hiroshi Tsutsumi; Noriyuki Kasagi; Itaru Hamachi

doi:10.1016/j.tetlet.2005.03.094

Suzuki coupling for protein modification

Akio Ojida, Hiroshi Tsutsumi, Noriyuki Kasagi, Itaru Hamachi

Molecular Bioinformatics

Research output: Contribution to journal › Article › peer-review

66 Citations (Scopus)

Abstract

Suzuki-coupling, a representative cross-coupling reaction between small molecules, can proceed on a protein surface in aqueous solution under mild conditions. The modified protein produced by the coupling reaction maintained its native like structure and function. In addition, fluorescent dye appended-protein acts as a fluorescent biosensor.

Original language	English
Pages (from-to)	3301-3305
Number of pages	5
Journal	Tetrahedron Letters
Volume	46
Issue number	19
DOIs	https://doi.org/10.1016/j.tetlet.2005.03.094
Publication status	Published - May 9 2005

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/j.tetlet.2005.03.094

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title = "Suzuki coupling for protein modification",

abstract = "Suzuki-coupling, a representative cross-coupling reaction between small molecules, can proceed on a protein surface in aqueous solution under mild conditions. The modified protein produced by the coupling reaction maintained its native like structure and function. In addition, fluorescent dye appended-protein acts as a fluorescent biosensor.",

author = "Akio Ojida and Hiroshi Tsutsumi and Noriyuki Kasagi and Itaru Hamachi",

year = "2005",

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T1 - Suzuki coupling for protein modification

AU - Ojida, Akio

AU - Tsutsumi, Hiroshi

AU - Kasagi, Noriyuki

AU - Hamachi, Itaru

PY - 2005/5/9

Y1 - 2005/5/9

N2 - Suzuki-coupling, a representative cross-coupling reaction between small molecules, can proceed on a protein surface in aqueous solution under mild conditions. The modified protein produced by the coupling reaction maintained its native like structure and function. In addition, fluorescent dye appended-protein acts as a fluorescent biosensor.

AB - Suzuki-coupling, a representative cross-coupling reaction between small molecules, can proceed on a protein surface in aqueous solution under mild conditions. The modified protein produced by the coupling reaction maintained its native like structure and function. In addition, fluorescent dye appended-protein acts as a fluorescent biosensor.

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U2 - 10.1016/j.tetlet.2005.03.094

DO - 10.1016/j.tetlet.2005.03.094

M3 - Article

AN - SCOPUS:17144406334

SN - 0040-4039

VL - 46

SP - 3301

EP - 3305

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 19

ER -

Suzuki coupling for protein modification

Abstract

All Science Journal Classification (ASJC) codes

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