Suzuki coupling for protein modification

Akio Ojida, Hiroshi Tsutsumi, Noriyuki Kasagi, Itaru Hamachi

Research output: Contribution to journalArticle

65 Citations (Scopus)

Abstract

Suzuki-coupling, a representative cross-coupling reaction between small molecules, can proceed on a protein surface in aqueous solution under mild conditions. The modified protein produced by the coupling reaction maintained its native like structure and function. In addition, fluorescent dye appended-protein acts as a fluorescent biosensor.

Original languageEnglish
Pages (from-to)3301-3305
Number of pages5
JournalTetrahedron Letters
Volume46
Issue number19
DOIs
Publication statusPublished - May 9 2005

Fingerprint

Cross Reactions
Biosensing Techniques
Fluorescent Dyes
Biosensors
Membrane Proteins
Proteins
Molecules

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

Suzuki coupling for protein modification. / Ojida, Akio; Tsutsumi, Hiroshi; Kasagi, Noriyuki; Hamachi, Itaru.

In: Tetrahedron Letters, Vol. 46, No. 19, 09.05.2005, p. 3301-3305.

Research output: Contribution to journalArticle

Ojida, A, Tsutsumi, H, Kasagi, N & Hamachi, I 2005, 'Suzuki coupling for protein modification', Tetrahedron Letters, vol. 46, no. 19, pp. 3301-3305. https://doi.org/10.1016/j.tetlet.2005.03.094
Ojida, Akio ; Tsutsumi, Hiroshi ; Kasagi, Noriyuki ; Hamachi, Itaru. / Suzuki coupling for protein modification. In: Tetrahedron Letters. 2005 ; Vol. 46, No. 19. pp. 3301-3305.
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