Synergistic electro-mechanical transfection for in-vivo regenerative therapy using electrically-induced microbubbles

Akiho Hirao, Keiko Miwa, Yasuhiro Moriizumi, Yoko Yamanishi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We have achieved permeabilization of adherent cells and gene transfer into them with a novel method using electrically-induced microbubbles [1]. Our technology has three remarkable points: (1) There is no safety concern which viral vectors always have. (2) Local permeabilization of living tissue can be achieved efficiently with minimal-invasiveness. (3) The size of the device is small and will be conveniently applied to a living body. This technology will contribute to realization of in-vivo regenerative therapy.

Original languageEnglish
Title of host publication23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
PublisherChemical and Biological Microsystems Society
Pages882-883
Number of pages2
ISBN (Electronic)9781733419000
Publication statusPublished - 2019
Event23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 - Basel, Switzerland
Duration: Oct 27 2019Oct 31 2019

Publication series

Name23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019

Conference

Conference23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
Country/TerritorySwitzerland
CityBasel
Period10/27/1910/31/19

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Chemical Engineering (miscellaneous)

Fingerprint

Dive into the research topics of 'Synergistic electro-mechanical transfection for in-vivo regenerative therapy using electrically-induced microbubbles'. Together they form a unique fingerprint.

Cite this