Syntheses and self-assembling behaviors of pentagonal conjugates of tryptophane zipper-forming peptide

Kazunori Matsuura, Kazuya Murasato, Nobuo Kimizuka

    Research output: Contribution to journalArticlepeer-review

    10 Citations (Scopus)

    Abstract

    Pentagonal conjugates of tryptophane zipper-forming peptide (CKTWTWTE) with a pentaazacyclopentadecane core (Pentagonal-Gly-Trpzip and Pentagonal-Ala-Trpzip) were synthesized and their self-assembling behaviors were investigated in water. Pentagonal-Gly-Trpzip self-assembled into nanofibers with the width of about 5 nm in neutral water (pH 7) via formation of tryptophane zipper, which irreversibly converted to nanoribbons by heating. In contrast, Pentagonal-Ala-Trpzip formed irregular aggregates in water.

    Original languageEnglish
    Pages (from-to)5187-5199
    Number of pages13
    JournalInternational journal of molecular sciences
    Volume12
    Issue number8
    DOIs
    Publication statusPublished - Aug 2011

    All Science Journal Classification (ASJC) codes

    • Catalysis
    • Molecular Biology
    • Spectroscopy
    • Computer Science Applications
    • Physical and Theoretical Chemistry
    • Organic Chemistry
    • Inorganic Chemistry

    Fingerprint Dive into the research topics of 'Syntheses and self-assembling behaviors of pentagonal conjugates of tryptophane zipper-forming peptide'. Together they form a unique fingerprint.

    Cite this