Abstract
It has become possible to synthesize all possible calix[6]arene derivatives with MeO-and ROCOCH2O- substituents from corresponding O-methylated calix[6]arenes(2-7). The yields of these reactions were relatively high and the products could be easily purified because of the absence of other regioisomers. They are one mono-, three di-, three tri-, three tetra-, one penta-, and one hexa-EtOCOCH2O-substituted products. It was proved that O-methylation products act as useful basic skeletons to design functionalized calix[6]arenes with the desired number of ROCOCH2O substituents and the regioselectively-positioned ROCOCH2O groups.
Original language | English |
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Pages (from-to) | 8757-8770 |
Number of pages | 14 |
Journal | Tetrahedron |
Volume | 51 |
Issue number | 32 |
DOIs | |
Publication status | Published - Aug 7 1995 |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Drug Discovery
- Organic Chemistry