Twenty-eight 1-ethyl- and l-p ropyl-5-substituted im idazoles were synthesized and their bleaching activity was evaluated by using the lettuce seedling test. 5-Phenyl- 1-propylim idazole (1) caused distinct chlorosis, while none of the compounds with various alkenyl groups at the 5-position of the imidazole ring showed this bleaching activity. Introduction of a bromo, chloro, fluoro, methyl or trifluorom ethyl group at the 4-position on the benzene ring of compound 1 increased the activity in comparison with that of compound 1. 5-[4-(3-Chlorobenzyloxy) phenyl]-l-ethylim idazole (15) and l-ethyl-5-[4-(3-m ethylbenzyloxy)phenyl]im idazole (21), analogs with a large substituent a t the 4-position on the benzene ring, also caused pronounced chlorosis in the lettuce seedlings. Both compounds 1 and 15 at 30 ppm decreased total carotenoid content in the lettuce seedlings to less than 40% of that in the control, and the reduction of total carotenoid content correlated well with treatment dose.
|Number of pages||6|
|Journal||Zeitschrift fur Naturforschung - Section C Journal of Biosciences|
|Publication status||Published - Jan 1 1993|
All Science Journal Classification (ASJC) codes
- Biochemistry, Genetics and Molecular Biology(all)