Synthesis and lateral root-inducing activity of novel 2-piperidones with a 1,4-benzodioxan ring

Hidetaka Tsukada, Naotaka Yamada, Eiji Taniguchi, Eiichi Kuwano

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A series of novel N-benzyl-2-piperidones having a 1,4-benzodioxan ring was synthesized and investigated for their activity to induce lateral roots in the lettuce seedlings. N-Benzyl-3-[1-(3,6-benzodioxanyl)-1-hydroxymethyl]-2-piperidone (23) induced 100% emergence of lateral roots at 100 ppm. There was no significant difference in activity between the erythro-arid threo-23. The introduction of a benzyloxymethyl substituent at the 2-position on the 1,4-benzodioxan ring slightly increased the activity compared with that of 23, showing some activity even at 1 ppm, while the activity was found to fall off sharply with a methoxy group adjacent to the 1,4-dioxane ring.

Original languageEnglish
Pages (from-to)317-328
Number of pages12
JournalJournal of the Faculty of Agriculture, Kyushu University
Issue number3-4
Publication statusPublished - Feb 1 2000


All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Agronomy and Crop Science

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