Synthesis and lateral root-inducing activity of novel n-substituted-2-piperidones with a 1,4-benzodioxan ring

Hidetaka Tsukada, Naotaka Yamada, Eiji Taniguchi, Eiichi Kuwano

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Novel N-substituted-2-piperidones with a 1,4-benzodioxan ring were prepared and evaluated for their activity to induce lateral roots in lettuce seedlings. Compounds were obtained by aldol condensation of the lithium enolate of N-substituted-2-piperidones with 1,4-benzodioxan-6-carbaldehyde. Of the series compounds tested, N-cinnamyl-3-[1-(1,4-benzodioxan-6-yl)-1-hydroxymethyl]-2-piperidone (2e) had the highest activity. In seedlings treated with 10 ppm of 2e, all of the primary roots formed lateral roots. Only erythro-2e showed lateral root-inducing activity, while threo-2e was inactive.

Original languageEnglish
Pages (from-to)2229-2231
Number of pages3
JournalBioscience, Biotechnology and Biochemistry
Issue number10
Publication statusPublished - Jan 1 2000


All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

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