Synthesis and Plant Growth-Inhibiting Activity of Pyridine derivatives

Hidetaka Tsukada, Naoto Kobayashi, Naotaka Yamada, Eiji Taniguchi, Eiichi Kuwano

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Abstract

A number of 3-pyridyl-2-propenoic acid derivatives, pyridines possessing a γ-butyrolactone ring and related compounds were synthesized and evaluated for their activity by using a lettuce seedling test. Most of the pyridine derivatives inhibited the growth of lettuce seedlings at concentrations ranging from 10 to 100 ppm. In the pyridine analogs of cinnamic acid, the 4-pyridine analog is more active than the 2- and 3-isomers. Of the 3-(4-pyridyl)propenoic acid derivatives examined, the N, N-diethyl-3-(4-pyridyl)-2-propenamide 3c-3 was the most active, which caused more than 90% inhibition of the hypocotyl and root growth at 50 ppm. Pyridine analogs with a 1,4-butanediol showed activity comparable to that of pyridyl γ-butyrolactone compounds, suggesting that the presence of the γ-butyrolactone was dispensable for the activity.

Original languageEnglish
Pages (from-to)169-180
Number of pages12
JournalJournal of the Faculty of Agriculture, Kyushu University
Volume43
Issue number1-2
Publication statusPublished - Nov 1998

All Science Journal Classification (ASJC) codes

  • Agricultural and Biological Sciences (miscellaneous)

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