Abstract
Novel purine nucleosides with a N-tert-butylhydroxylamino group at the 2-position of purine nucleus (1-3) were synthesized, which might prefer anti conformation and would not perturb DNA structure when incorporated into oligonucleotide. Oxidation of 1-3 by treatment with Ag2O or air afforded stable aminoxyl radicals (1'-3') and their properties were studied by EPR spectroscopy. 5-N-tert-butylhydroxylamino uridine (4) was also synthesized.
Original language | English |
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Pages (from-to) | 139-140 |
Number of pages | 2 |
Journal | Nucleic acids research. Supplement (2001) |
Issue number | 2 |
DOIs | |
Publication status | Published - 2002 |