Synthesis and reactions of 5-tributylstannyl-4-fluoro-1H-pyrazole

Takeshi Hanamoto; Takao Suetake; Yukinori Koga; Toshio Kawanami; Hiroshi Furuno; Junji Inanaga

doi:10.1016/j.tet.2007.03.117

Synthesis and reactions of 5-tributylstannyl-4-fluoro-1H-pyrazole

Takeshi Hanamoto, Takao Suetake, Yukinori Koga, Toshio Kawanami, Hiroshi Furuno, Junji Inanaga

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Abstract

The palladium-catalyzed cross-coupling reactions of 5-tributylstannyl-4-fluoro-1H-pyrazole with aryl iodides provided high yields of the corresponding 5-aryl-4-fluoro-1H-pyrazoles. Furthermore, these cross-coupling reactions proceeded smoothly under an atmosphere of carbon monoxide (CO) to afford the corresponding 5-acyl-4-fluoro-1H-pyrazoles as CO-insertion products.

Original language	English
Pages (from-to)	5062-5070
Number of pages	9
Journal	Tetrahedron
Volume	63
Issue number	23
DOIs	https://doi.org/10.1016/j.tet.2007.03.117
Publication status	Published - Jun 4 2007

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/j.tet.2007.03.117

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abstract = "The palladium-catalyzed cross-coupling reactions of 5-tributylstannyl-4-fluoro-1H-pyrazole with aryl iodides provided high yields of the corresponding 5-aryl-4-fluoro-1H-pyrazoles. Furthermore, these cross-coupling reactions proceeded smoothly under an atmosphere of carbon monoxide (CO) to afford the corresponding 5-acyl-4-fluoro-1H-pyrazoles as CO-insertion products.",

author = "Takeshi Hanamoto and Takao Suetake and Yukinori Koga and Toshio Kawanami and Hiroshi Furuno and Junji Inanaga",

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T1 - Synthesis and reactions of 5-tributylstannyl-4-fluoro-1H-pyrazole

AU - Hanamoto, Takeshi

AU - Suetake, Takao

AU - Koga, Yukinori

AU - Kawanami, Toshio

AU - Furuno, Hiroshi

AU - Inanaga, Junji

PY - 2007/6/4

Y1 - 2007/6/4

N2 - The palladium-catalyzed cross-coupling reactions of 5-tributylstannyl-4-fluoro-1H-pyrazole with aryl iodides provided high yields of the corresponding 5-aryl-4-fluoro-1H-pyrazoles. Furthermore, these cross-coupling reactions proceeded smoothly under an atmosphere of carbon monoxide (CO) to afford the corresponding 5-acyl-4-fluoro-1H-pyrazoles as CO-insertion products.

AB - The palladium-catalyzed cross-coupling reactions of 5-tributylstannyl-4-fluoro-1H-pyrazole with aryl iodides provided high yields of the corresponding 5-aryl-4-fluoro-1H-pyrazoles. Furthermore, these cross-coupling reactions proceeded smoothly under an atmosphere of carbon monoxide (CO) to afford the corresponding 5-acyl-4-fluoro-1H-pyrazoles as CO-insertion products.

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VL - 63

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JO - Tetrahedron

JF - Tetrahedron

IS - 23

ER -

Synthesis and reactions of 5-tributylstannyl-4-fluoro-1H-pyrazole

Abstract

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