Synthesis and reactivity of 2-aminoethanethiolato-bridged dinuclear Ru(hmb) complexes (hmb = η6-hexamethylbenzene): Mechanistic consideration on transfer hydrogenation with bifunctional [RuCl 2(hmb)]2/2-aminoethanethiol catalyst system

Masato Ito, Akira Watanabe, Yuji Shibata, Takao Ikariya

Research output: Contribution to journalArticle

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A series of dinuclear Ru(hmb) complexes with a bridging 2-aminoethanethiolato ligand (S-NH) have been newly prepared by controlling the stoichiometry of starting materials. Their catalytic performance in the racemization of an optically pure secondary alcohol indicated that the relative proportion of the Ru(hmb) and the S-NH unit in these catalyst precursors in addition to the amount of base as an activating agent is crucially important to generate a catalytically active species. Moreover, chiral versions of dinuclear Ru(S-NH)(hmb) complexes displayed excellent catalytic performance in terms of reactivity and enantioselectivity for the asymmetric transfer hydrogenation of aromatic ketones using HCO2H-N(C2H5) 3. In agreement with these results, the crossover experiment using a symmetrically bridged dinuclear complex, [Ru(μ-SCH2CH 2NH2)(hmb)]2Cl2, and its Cp*Ir dinuclear congener, [Cp*Ir(μ-SCH2CH2NH 2)]2Cl2 (Cp* = η5-C 5(CH3)5), suggested that the catalytic performance in the hydrogen transfer is originated from the mononuclear amido complex Ru(SCH2CH2NH)(hmb) bearing a Ru/NH bifunctionality.

Original languageEnglish
Pages (from-to)4584-4592
Number of pages9
Issue number20
Publication statusPublished - Oct 25 2010
Externally publishedYes


All Science Journal Classification (ASJC) codes

  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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