Abstract
Viruses are natural supramolecular nanocapsules self-assembled from the constituent proteins. For example, a kind of spherical virus, tomato bushy stunt virus, is formed from C3-symmetric β-sheet proteins. We previously reported synthesis of a C3-symmetric peptide conjugate which bear three CFKFEFKFE peptide chains. These peptide chains have potential to form anti-parallel β-sheets, and the conjugate formed spherical nanostructures in acidic water. In this study, we describe synthesis and aggregate characteristics of an improved C3-symmetric peptide conjugate which bear three CFKFKFKFK peptide. The cationic 3-way peptide conjugate was successively dissolved in neutral water and formation of spherical aggregates was observed by AFM.
| Original language | English |
|---|---|
| Title of host publication | 54th SPSJ Annual Meeting 2005 - Polymer Preprints, Japan |
| Pages | 2050 |
| Number of pages | 1 |
| Volume | 54 |
| Edition | 1 |
| Publication status | Published - 2005 |
| Event | 54th SPSJ Annual Meeting 2005 - Yokohama, Japan Duration: May 25 2005 → May 27 2005 |
Other
| Other | 54th SPSJ Annual Meeting 2005 |
|---|---|
| Country | Japan |
| City | Yokohama |
| Period | 5/25/05 → 5/27/05 |
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All Science Journal Classification (ASJC) codes
- Engineering(all)
Cite this
Synthesis and self-assembly of C3-symmetric basic peptide conjugates. / Kawaharada, Aiko; Murasato, Kazuya; Matsuura, Kazunori; Kimizuka, Nobuo.
54th SPSJ Annual Meeting 2005 - Polymer Preprints, Japan. Vol. 54 1. ed. 2005. p. 2050.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Synthesis and self-assembly of C3-symmetric basic peptide conjugates
AU - Kawaharada, Aiko
AU - Murasato, Kazuya
AU - Matsuura, Kazunori
AU - Kimizuka, Nobuo
PY - 2005
Y1 - 2005
N2 - Viruses are natural supramolecular nanocapsules self-assembled from the constituent proteins. For example, a kind of spherical virus, tomato bushy stunt virus, is formed from C3-symmetric β-sheet proteins. We previously reported synthesis of a C3-symmetric peptide conjugate which bear three CFKFEFKFE peptide chains. These peptide chains have potential to form anti-parallel β-sheets, and the conjugate formed spherical nanostructures in acidic water. In this study, we describe synthesis and aggregate characteristics of an improved C3-symmetric peptide conjugate which bear three CFKFKFKFK peptide. The cationic 3-way peptide conjugate was successively dissolved in neutral water and formation of spherical aggregates was observed by AFM.
AB - Viruses are natural supramolecular nanocapsules self-assembled from the constituent proteins. For example, a kind of spherical virus, tomato bushy stunt virus, is formed from C3-symmetric β-sheet proteins. We previously reported synthesis of a C3-symmetric peptide conjugate which bear three CFKFEFKFE peptide chains. These peptide chains have potential to form anti-parallel β-sheets, and the conjugate formed spherical nanostructures in acidic water. In this study, we describe synthesis and aggregate characteristics of an improved C3-symmetric peptide conjugate which bear three CFKFKFKFK peptide. The cationic 3-way peptide conjugate was successively dissolved in neutral water and formation of spherical aggregates was observed by AFM.
UR - http://www.scopus.com/inward/record.url?scp=33645648907&partnerID=8YFLogxK
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M3 - Conference contribution
AN - SCOPUS:33645648907
VL - 54
SP - 2050
BT - 54th SPSJ Annual Meeting 2005 - Polymer Preprints, Japan
ER -