Synthesis and self-assembly of C3-symmetric basic peptide conjugates

Aiko Kawaharada, Kazuya Murasato, Kazunori Matsuura, Nobuo Kimizuka

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Viruses are natural supramolecular nanocapsules self-assembled from the constituent proteins. For example, a kind of spherical virus, tomato bushy stunt virus, is formed from C3-symmetric β-sheet proteins. We previously reported synthesis of a C3-symmetric peptide conjugate which bear three CFKFEFKFE peptide chains. These peptide chains have potential to form anti-parallel β-sheets, and the conjugate formed spherical nanostructures in acidic water. In this study, we describe synthesis and aggregate characteristics of an improved C3-symmetric peptide conjugate which bear three CFKFKFKFK peptide. The cationic 3-way peptide conjugate was successively dissolved in neutral water and formation of spherical aggregates was observed by AFM.

Original languageEnglish
Title of host publication54th SPSJ Annual Meeting 2005 - Polymer Preprints, Japan
Pages2050
Number of pages1
Volume54
Edition1
Publication statusPublished - 2005
Event54th SPSJ Annual Meeting 2005 - Yokohama, Japan
Duration: May 25 2005May 27 2005

Other

Other54th SPSJ Annual Meeting 2005
CountryJapan
CityYokohama
Period5/25/055/27/05

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Self assembly
Peptides
Viruses
Nanocapsules
Proteins
Water
Nanostructures

All Science Journal Classification (ASJC) codes

  • Engineering(all)

Cite this

Kawaharada, A., Murasato, K., Matsuura, K., & Kimizuka, N. (2005). Synthesis and self-assembly of C3-symmetric basic peptide conjugates. In 54th SPSJ Annual Meeting 2005 - Polymer Preprints, Japan (1 ed., Vol. 54, pp. 2050)

Synthesis and self-assembly of C3-symmetric basic peptide conjugates. / Kawaharada, Aiko; Murasato, Kazuya; Matsuura, Kazunori; Kimizuka, Nobuo.

54th SPSJ Annual Meeting 2005 - Polymer Preprints, Japan. Vol. 54 1. ed. 2005. p. 2050.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Kawaharada, A, Murasato, K, Matsuura, K & Kimizuka, N 2005, Synthesis and self-assembly of C3-symmetric basic peptide conjugates. in 54th SPSJ Annual Meeting 2005 - Polymer Preprints, Japan. 1 edn, vol. 54, pp. 2050, 54th SPSJ Annual Meeting 2005, Yokohama, Japan, 5/25/05.
Kawaharada A, Murasato K, Matsuura K, Kimizuka N. Synthesis and self-assembly of C3-symmetric basic peptide conjugates. In 54th SPSJ Annual Meeting 2005 - Polymer Preprints, Japan. 1 ed. Vol. 54. 2005. p. 2050
Kawaharada, Aiko ; Murasato, Kazuya ; Matsuura, Kazunori ; Kimizuka, Nobuo. / Synthesis and self-assembly of C3-symmetric basic peptide conjugates. 54th SPSJ Annual Meeting 2005 - Polymer Preprints, Japan. Vol. 54 1. ed. 2005. pp. 2050
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