Synthesis and self-assembly of C3-symmetric basic peptide conjugates

Aiko Kawaharada, Kazuya Murasato, Kazunori Matsuura, Nobuo Kimizuka

    Research output: Chapter in Book/Report/Conference proceedingConference contribution


    Viruses are natural supramolecular nanocapsules self-assembled from the constituent proteins. For example, a kind of spherical virus, tomato bushy stunt virus, is formed from C3-symmetric β-sheet proteins. We previously reported synthesis of a C3-symmetric peptide conjugate which bear three CFKFEFKFE peptide chains. These peptide chains have potential to form anti-parallel β-sheets, and the conjugate formed spherical nanostructures in acidic water. In this study, we describe synthesis and aggregate characteristics of an improved C3-symmetric peptide conjugate which bear three CFKFKFKFK peptide. The cationic 3-way peptide conjugate was successively dissolved in neutral water and formation of spherical aggregates was observed by AFM.

    Original languageEnglish
    Title of host publication54th SPSJ Annual Meeting 2005 - Polymer Preprints, Japan
    Number of pages1
    Publication statusPublished - 2005
    Event54th SPSJ Annual Meeting 2005 - Yokohama, Japan
    Duration: May 25 2005May 27 2005


    Other54th SPSJ Annual Meeting 2005

    All Science Journal Classification (ASJC) codes

    • Engineering(all)


    Dive into the research topics of 'Synthesis and self-assembly of C3-symmetric basic peptide conjugates'. Together they form a unique fingerprint.

    Cite this