Synthesis and self-assembly of C3-symmetric basic peptide conjugates

Aiko Kawaharada, Kazuya Murasato, Kazunori Matsuura, Nobuo Kimizuka

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Viruses are natural supramolecular nanocapsules self-assembled from the constituent proteins. For example, a kind of spherical virus, tomato bushy stunt virus, is formed from C3-symmetric β-sheet proteins. We previously reported synthesis of a C3-symmetric peptide conjugate which bear three CFKFEFKFE peptide chains. These peptide chains have potential to form anti-parallel β-sheets, and the conjugate formed spherical nanostructures in acidic water. In this study, we describe synthesis and aggregate characteristics of an improved C3-symmetric peptide conjugate which bear three CFKFKFKFK peptide. The cationic 3-way peptide conjugate was successively dissolved in neutral water and formation of spherical aggregates was observed by AFM.

Original languageEnglish
Title of host publication54th SPSJ Annual Meeting 2005 - Polymer Preprints, Japan
Pages2050
Number of pages1
Volume54
Edition1
Publication statusPublished - 2005
Event54th SPSJ Annual Meeting 2005 - Yokohama, Japan
Duration: May 25 2005May 27 2005

Other

Other54th SPSJ Annual Meeting 2005
CountryJapan
CityYokohama
Period5/25/055/27/05

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All Science Journal Classification (ASJC) codes

  • Engineering(all)

Cite this

Kawaharada, A., Murasato, K., Matsuura, K., & Kimizuka, N. (2005). Synthesis and self-assembly of C3-symmetric basic peptide conjugates. In 54th SPSJ Annual Meeting 2005 - Polymer Preprints, Japan (1 ed., Vol. 54, pp. 2050)