Synthesis and self-assembly of trigonal-type β-sheet-forming peptide conjugates

Kazunori Matsuura, Aiko Kawaharada, Kazuya Murasato, Nobuo Kimizuka

    Research output: Contribution to conferencePaperpeer-review

    Abstract

    Inspired by biological supramolecular self-assemblies such as viruses and clathrin, we have developed a C3-symmetric peptide conjugate bearing β-sheet forming peptides Trigonal(FKFE)2, which have spherical nano-assemblies in the acidic solution.2) In this study, we describe synthesis and self-assembly of basic peptide conjugate Trigonal(FKFK) 2. The nanostructures formed by self-assembly of Trigonal(FKFK) 2 depended on the pH and ionic strength of aqueous solution. Trigonal(FKFK)2 formed spherical assemblies in neutral water, whereas fibrous assemblies were formed in basic water.

    Original languageEnglish
    Number of pages1
    Publication statusPublished - Oct 19 2006
    Event55th SPSJ Annual Meeting - Nagoya, Japan
    Duration: May 24 2006May 26 2006

    Other

    Other55th SPSJ Annual Meeting
    Country/TerritoryJapan
    CityNagoya
    Period5/24/065/26/06

    All Science Journal Classification (ASJC) codes

    • Engineering(all)

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