Synthesis of 1,1′-binaphthyl-2,2′-diyl phosphoroselenoic amides and their conversion to optically pure phosphoramidites

Toshiaki Murai, Shinsuke Inaji, Ken Morishita, Fumitoshi Shibahara, Makoto Tokunaga, Yasushi Obora, Yasushi Tsuji

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)

Abstract

Optically pure phosphoroselenoyl chloride was reacted with racemic amines to give phosphoroselenoic amides as two diastereomeric mixtures in high yields. The diastereomeric mixtures were separated by fractional recrystallization or by chromatography. Extrusion of the selenium atom from the separated amides led to diastereomerically pure phosphoramidites. The ability of the obtained amidites to act as optically active ligands was tested in the hydrogenation of an imine.

Original languageEnglish
Pages (from-to)1424-1425
Number of pages2
JournalChemistry Letters
Volume35
Issue number12
DOIs
Publication statusPublished - Dec 5 2006
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

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