TY - JOUR
T1 - Synthesis of 4-quinolones through nickel-catalyzed intramolecular amination on the β-carbon of o-(N-alkylamino)propiophenones
AU - Ueno, Satoshi
AU - Shimizu, Ryosuke
AU - Maeda, Ryohei
AU - Kuwano, Ryoichi
N1 - Copyright:
Copyright 2012 Elsevier B.V., All rights reserved.
PY - 2012
Y1 - 2012
N2 - o-(N-Alkylamino)propiophenones are converted into 4-quinolones in the presence of chlorobenzene, potassium phosphate, morpholine, and nickel(0) catalyst. The reaction proceeds through the nickel-catalyzed formation of β-enaminones from o-(N-alkylamino)propiophenones and morpholine, followed by the intramolecular transamination.
AB - o-(N-Alkylamino)propiophenones are converted into 4-quinolones in the presence of chlorobenzene, potassium phosphate, morpholine, and nickel(0) catalyst. The reaction proceeds through the nickel-catalyzed formation of β-enaminones from o-(N-alkylamino)propiophenones and morpholine, followed by the intramolecular transamination.
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U2 - 10.1055/s-0031-1291146
DO - 10.1055/s-0031-1291146
M3 - Article
AN - SCOPUS:84862152692
VL - 23
SP - 1639
EP - 1642
JO - Synlett
JF - Synlett
SN - 0936-5214
IS - 11
ER -