Synthesis of [5]helicenes with a substituent exclusively on the interior side of the helix by metal-catalyzed cycloisomerization

Kosuke Yamamoto, Mieko Okazumi, Hiroshi Suemune, Kazuteru Usui

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[5]Helicenes with a substituent exclusively oriented toward the interior curvature of the helix are synthesized by metal-catalyzed cycloisomerization. In addition, novel azulene-fused helicenes have been found through cycloisomerization studies. These [5]helicenes shows a high enough configurationally stability to allow resolution by HPLC on a chiral stationary phase.

Original languageEnglish
Pages (from-to)1806-1809
Number of pages4
JournalOrganic Letters
Issue number8
Publication statusPublished - Apr 19 2013


All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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