Abstract
The 61-bis(1-adamantylcarbamoyl)-1,2-methano[60]fullerene was synthesized from N,N′-di(1-adamantyl)malondiamide and C 60 in the presence of 1,8-diazabicyclo[5,4,0]-7-undecene. The intraperitoneal administration of this fullerene derivative (10 mg/kg) caused an antagonistic effect on haloperidol-induced catalepsy in mice.
Original language | English |
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Pages (from-to) | 5619-5621 |
Number of pages | 3 |
Journal | Bioorganic and Medicinal Chemistry Letters |
Volume | 14 |
Issue number | 22 |
DOIs | |
Publication status | Published - Nov 15 2004 |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Molecular Medicine
- Molecular Biology
- Pharmaceutical Science
- Drug Discovery
- Clinical Biochemistry
- Organic Chemistry