Synthesis of bioactive ormosils by the sol-gel method

K. Tsuru, C. Ohtsuki, A. Osaka, T. Iwamoto, J. D. Mackenzie

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12 Citations (Scopus)


Bioactive ORMOSILS (Organically Modified Silicates) were synthesized by a sol-gel method, with tetraethoxysilane (TEOS) and polydimethylsiloxane (PDMS). Ca(II) ions were incorporated into the ormosil monoliths by addition of calcium nitrate. The synthesized samples were examined on the bioactivity by the use of a simulated body fluid (the Kokubo solution). The Ca(II) containing ormosils were bioactive that deposited apatite during soaking in the Kokubo solution. The dissolution of Ca(II) from the sample favored the formation of the hydrated silica, which gave nucleation sites for apatite, while the effect of dissolved Ca(II) ions to increase the degree of supersaturation in the fluid could not be neglected.

Original languageEnglish
Pages (from-to)403-408
Number of pages6
JournalUnknown Journal
Publication statusPublished - 1996
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials


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