Synthesis of blood compatible PDMS-based organic-inorganic hybrid coatings

Takeshi Yabuta, Kanji Tsuru, Satoshi Hayakawa, Akiyoshi Osaka

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Abstract

PDMS-TiO2 hybrid coating sols were prepared from silanol-terminated polydimethylsiloxane and titanium tetraisopropoxide through sol-gel process. The coating sols were developed on stainless steel substrate with dip-coating technique. The surface structure of the hybrid coating was characterized by Fourier transform infrared (FT-IR) analysis, contact angle, and surface free energy on the hybrid coating. Blood compatibility was also evaluated in terms of blood clotting time and platelet adhesion. The hybrid coatings have high contact angles and low surface free energies compared to coating-free metal surface. The blood clotting properties were not affected by the hybrid coatings but the platelet adhesion was depressed to less than 1/20 as much as that for the coating-free substrate.

Original languageEnglish
Pages (from-to)273-276
Number of pages4
JournalJournal of Sol-Gel Science and Technology
Volume31
Issue number1-3 SPEC.ISS.
DOIs
Publication statusPublished - Aug 1 2004

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All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Biomaterials
  • Condensed Matter Physics
  • Materials Chemistry

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