The double [4+2] cycloadditions between fullerene and steroid- appended dibenzoates 7 and 8, the reaction sites of which were controlled by diols in chiral template molecules, afforded fullerene-steroid bisadducts 11 and 12 regio- and chiroselectively. CD spectroscopic studies of 11 and 12 indicated that the magnitude of the cotton effects changes reflecting the chiral structure of the steroid moiety in 11 and 12.
All Science Journal Classification (ASJC) codes
- Drug Discovery
- Organic Chemistry