Synthesis of gene carrier responding with tyrosine kinase 'c-Src' and functional control

Keiko Terada; Yuko Sato; Jun Ohishi; Kenji Kawamura; Jeong Hun Kang; Daisuke Asai; Yoshiki Katayama

Synthesis of gene carrier responding with tyrosine kinase 'c-Src' and functional control

Keiko Terada, Yuko Sato, Jun Ohishi, Kenji Kawamura, Jeong Hun Kang, Daisuke Asai, Yoshiki Katayama

Research output: Contribution to conference › Paper › peer-review

Abstract

We designed a gene carrier that can activate the delivered gene in response to the intercellular kinase signal. 'c-Src', which is non-receptor tyrosine kinase, is specifically activated within a cancer cell. We create gene carrier to express a therapeutics gene in response to 'c-Src'. We synthesize polymers that are grafted c-Src substrate peptide as an intercellular signal-response gene carrier. We will discuss the design of c-Src responsive carriers and their abilities for target signal specific gene regulation.

Original language	English
Number of pages	1
Publication status	Published - Oct 19 2006
Event	55th SPSJ Annual Meeting - Nagoya, Japan Duration: May 24 2006 → May 26 2006

Other

Other	55th SPSJ Annual Meeting
Country/Territory	Japan
City	Nagoya
Period	5/24/06 → 5/26/06

All Science Journal Classification (ASJC) codes

Engineering(all)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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abstract = "We designed a gene carrier that can activate the delivered gene in response to the intercellular kinase signal. 'c-Src', which is non-receptor tyrosine kinase, is specifically activated within a cancer cell. We create gene carrier to express a therapeutics gene in response to 'c-Src'. We synthesize polymers that are grafted c-Src substrate peptide as an intercellular signal-response gene carrier. We will discuss the design of c-Src responsive carriers and their abilities for target signal specific gene regulation.",

author = "Keiko Terada and Yuko Sato and Jun Ohishi and Kenji Kawamura and Kang, {Jeong Hun} and Daisuke Asai and Yoshiki Katayama",

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T1 - Synthesis of gene carrier responding with tyrosine kinase 'c-Src' and functional control

AU - Terada, Keiko

AU - Sato, Yuko

AU - Ohishi, Jun

AU - Kawamura, Kenji

AU - Kang, Jeong Hun

AU - Asai, Daisuke

AU - Katayama, Yoshiki

PY - 2006/10/19

Y1 - 2006/10/19

N2 - We designed a gene carrier that can activate the delivered gene in response to the intercellular kinase signal. 'c-Src', which is non-receptor tyrosine kinase, is specifically activated within a cancer cell. We create gene carrier to express a therapeutics gene in response to 'c-Src'. We synthesize polymers that are grafted c-Src substrate peptide as an intercellular signal-response gene carrier. We will discuss the design of c-Src responsive carriers and their abilities for target signal specific gene regulation.

AB - We designed a gene carrier that can activate the delivered gene in response to the intercellular kinase signal. 'c-Src', which is non-receptor tyrosine kinase, is specifically activated within a cancer cell. We create gene carrier to express a therapeutics gene in response to 'c-Src'. We synthesize polymers that are grafted c-Src substrate peptide as an intercellular signal-response gene carrier. We will discuss the design of c-Src responsive carriers and their abilities for target signal specific gene regulation.

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M3 - Paper

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T2 - 55th SPSJ Annual Meeting

Y2 - 24 May 2006 through 26 May 2006

ER -

Synthesis of gene carrier responding with tyrosine kinase 'c-Src' and functional control

Abstract

Other

All Science Journal Classification (ASJC) codes

UN SDGs

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