Synthesis of multisubstituted furans, pyrroles, and thiophenes via ynolates

Mitsuru Shindo, Yutaka Yoshimura, Maiko Hayashi, Hiroe Soejima, Takashi Yoshikawa, Kenji Matsumoto, Kozo Shishido

Research output: Contribution to journalArticlepeer-review

82 Citations (Scopus)

Abstract

An efficient synthetic method for the preparation of multisubstituted furans, thiophenes, and pyrroles using ynolates was developed. This novel formal [4 + 1] annulation by C2-C3 and C3-C4 bond formations Includes cycloaddition, cyclization, decarboxylation, and dehydration as key steps.

Original languageEnglish
Pages (from-to)1963-1966
Number of pages4
JournalOrganic letters
Volume9
Issue number10
DOIs
Publication statusPublished - May 10 2007

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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