Synthesis of Optically Active 1,3,2-Oxazaphospholidine 2-Sulfides and 1,3,2-Benzodioxaphosphorin 2-Sulfides

Shao Yong Wu, Akinori Hirashima, Eiichi Kuwano, Morifusa Eto

Research output: Contribution to journalArticle

Abstract

The optical isomers of ten kinds of insecticidal 1,3,2-oxazaphospholidine 2-sulfides (OS) and two kinds of 1,3,2-benzodioxaphosphorin 2-sulfides (BS), including the commercial insecticide salithion, were synthesized in high optical purity by using two optically active aryl methyl phosphorochloridothionates (AMPC) as chiral two-step phosphorylating reagents. Their configurations were assigned according to the reaction mechanisms and supported by proton NMR information.

Original languageEnglish
Pages (from-to)537-547
Number of pages11
JournalAgricultural and Biological Chemistry
Volume51
Issue number2
DOIs
Publication statusPublished - Jan 1 1987

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Sulfides
sulfides
synthesis
reaction mechanisms
Insecticides
Isomers
purity
protons
isomers
Protons
insecticides
Nuclear magnetic resonance
(1,3,2)oxazaphospholidine
salithion

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

Cite this

Synthesis of Optically Active 1,3,2-Oxazaphospholidine 2-Sulfides and 1,3,2-Benzodioxaphosphorin 2-Sulfides. / Wu, Shao Yong; Hirashima, Akinori; Kuwano, Eiichi; Eto, Morifusa.

In: Agricultural and Biological Chemistry, Vol. 51, No. 2, 01.01.1987, p. 537-547.

Research output: Contribution to journalArticle

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