Synthesis of phosphorofluoridate analogues of myo-inositol 1,4,5-tris(phosphate) and their biological activity

Yutaka Watanabe, Shinsuke Sofue, Shoichiro Ozaki, Masato Hirata

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Phosphorofluoridate analogues of myo-inositol 1,4,5-tris(phosphate), 4- and 5-phosphorofluoridate and 4,5-bis(phosphorofluoridate), were prepared and their biological activity towards InsP3 5-phosphatase was found to be similar to or more active than that for InsP3 while they proved to be less active in the binding assay than InsP3.

Original languageEnglish
Pages (from-to)1815-1816
Number of pages2
JournalChemical Communications
Issue number15
DOIs
Publication statusPublished - Jan 1 1996

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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