Synthesis of the ABC and IJ ring fragments of yessotoxin

Tohru Oishi, Miho Suzuki, Koji Watanabe, Michio Murata

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Synthesis of a 6/6/6 tricyclic ether system (3) corresponding to the ABC ring fragment of yessotoxin (1) has been achieved via coupling of a triflate and a 2-lithiofuran followed by intramolecular hetero-Michael addition. The IJ ring fragment (4) of 1 was readily synthesized via successive Sharpless epoxidation and 6-endo cyclization of the resulting vinyl epoxide.

Original languageEnglish
Pages (from-to)3975-3978
Number of pages4
JournalTetrahedron Letters
Volume47
Issue number24
DOIs
Publication statusPublished - Jun 12 2006
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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