Synthesis of the DFGH ring system of type B physalins: Highly oxygenated, cage-shaped molecules

Megumi Ohkubo, Go Hirai, Mikiko Sodeoka

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Let the dominos fall: Synthesis of the complex DFGH ring system of the title compounds has been accomplished. The approach features simple treatment of the key intermediate with a Brønsted base to afford the tetracyclic cage-shaped target in one pot through a four-step domino transformation (see scheme; Mc= monochloromesylate, MOM=methoxymethyl).

Original languageEnglish
Pages (from-to)3862-3866
Number of pages5
JournalAngewandte Chemie - International Edition
Volume48
Issue number21
DOIs
Publication statusPublished - May 11 2009
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)

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