Synthesis of transmembrane molecules by click chemistry

Wataru Hatanaka, Hiroki Takeuchi, Minaho Koga, Taka Aki Ryujin, Akihiro Kishimura, Yoshiki Katayama, Shinya Tsukiji, Takeshi Mori

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

We report here efficient synthesis of artificial transmembrane molecules (ATMs), via click chemistry of a transmembrane part and membrane-penetrating parts. Synthesized ATMs penetrated the cell membrane by Coulombic force, while they stayed on the cell membrane once they were complexed with streptavidin.

Original languageEnglish
Pages (from-to)433-436
Number of pages4
JournalChemistry Letters
Volume48
Issue number5
DOIs
Publication statusPublished - Jan 1 2019

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

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