Synthesis of Ynolates via Double Deprotonation of Nonbrominated Esters

Jun Sun, Toshiya Yoshiiwa, Takayuki Iwata, Mitsuru Shindo

Research output: Contribution to journalArticle

Abstract

Herein, we report a double deprotonation method used for the preparation of ynolates starting from nonbrominated 2,6-di-tert-butylphenyl esters. The current method is superior to the previously described double lithium/halogen exchange approach because easily accessible starting materials are used. This method will be especially useful for preparation of ynolates bearing functional groups in organic synthesis.

Original languageEnglish
Pages (from-to)6585-6588
Number of pages4
JournalOrganic letters
Volume21
Issue number17
DOIs
Publication statusPublished - Sep 6 2019

    Fingerprint

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Cite this