Synthesis, stereochemical stability, and biological activity of stemonamine and its related stemona alkaloids

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Abstract

More than 140 Stemona alkaloids have been isolated from Stemona plants (of the Stemonaceae species). These alkaloids represent a unique pyrrolo[1,2-a]azepine nucleus, and can be classified into eight groups on the basis of their chemical aspects. This study is focused on the synthesis of stemonamine group alkaloids, in addition to their chemical stability and biological activity.

Original languageEnglish
Pages (from-to)349-377
Number of pages29
JournalHeterocycles
Volume98
Issue number3
DOIs
Publication statusPublished - Jan 1 2019

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Stemonaceae
Bioactivity
Alkaloids
Azepines
Chemical stability
stemonamine

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

Cite this

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abstract = "More than 140 Stemona alkaloids have been isolated from Stemona plants (of the Stemonaceae species). These alkaloids represent a unique pyrrolo[1,2-a]azepine nucleus, and can be classified into eight groups on the basis of their chemical aspects. This study is focused on the synthesis of stemonamine group alkaloids, in addition to their chemical stability and biological activity.",
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