Synthetic chiral chromophoric bilayer membranes as chemical transducers: effect of alcohols on enhanced circular dichroism

Koji Nakano, Isamu Moriguchi, Naotoshi Nakashima, Makoto Takagi

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A bilayer-forming synthetic lipid containing a chiral centre and a chromophoric group was investigated as a spectroscopic transducer, based on its enhanced circular dichroism (CD). The CD intensity of chiral bilayers was reduced with addition of alcohol. For ten additives tested, a linear correlation was observed between the CD spectral response to the alcohols and their partition coefficient (log P) in octanol/water system. By use of an immobilization technique, the bilayer film was obtained on a quartz plate, and a possible application as a solid-phase assay of methanol was demonstrated.

Original languageEnglish
Pages (from-to)1933-1936
Number of pages4
JournalJournal of Materials Science
Issue number7
Publication statusPublished - Apr 1 1992


All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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