Synthetic studies and properties of N-tert-butylaminoxyl nucleosides.

Mariko Aso, Toshiyuki Kaneko, Morihide Nakamura, Yasuhiro Matsui, Noboru Koga, Hiroshi Suemune

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

We synthesized 5-N-tert-butylhydroxylamino-2'-deoxyuridine (9b) via lithium-halogen exchange reaction of sodium salt of 5-iodo-2'-deoxyuridine (8b). This procedure was applicable to synthesis of the corresponding uridine (9a) and N-benzoyl cytidine (13). Obtained 9b was converted into stable aminoxyl (5a) by treatment with Ag2O to study its properties as a novel spin-labeled nucleoside.

Original languageEnglish
Pages (from-to)9-10
Number of pages2
JournalNucleic acids research. Supplement (2001)
Issue number3
DOIs
Publication statusPublished - 2003

Fingerprint Dive into the research topics of 'Synthetic studies and properties of N-tert-butylaminoxyl nucleosides.'. Together they form a unique fingerprint.

Cite this