Systemic Necrotizing Vasculitis with Renal Involvement Accompanied by Remarkable Eosinophilia: A Case with Overlapping Features of Polyarteritis Nodosa and Allergic Granulomatous Angiitis.

Toshiyuki Sasaguri, Hirokazu Shiraishi, Hirokazu Date, Masayuki Takasugi, Masasuke Soejima, Yoshiyuki Hino, Akihide Tanimoto, Akio Horie

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

A 71-year-old woman was clinically suspected of allergic granulomatous angiitis (AGA) because of preceding allergic diseases including bronchial asthma, remarkable eosinophilia (14,300/mm3), mononeuritis multiplex, positive rheumatoid factor, elevated serum immunoglobulin E, and eosinophilic inflammation of the kidney. Autopsy findings, however, were characteristic of polyarteritis nodosa (PAN). Necrotizing angiitis was present in several organs except for the lung; focal and segmental glomerular lesions with crescent formation were observed in the kidney, and granuloma formation was not found. This case may be an intermediate type between PAN and AGA (an overlap syndrome) and provide useful information on the clinical entities of systemic necrotizing vasculitis.

Original languageEnglish
Pages (from-to)477-482
Number of pages6
JournalJapanese Journal of Medicine
Volume30
Issue number5
DOIs
Publication statusPublished - Jan 1 1991
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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