TY - JOUR
T1 - Systemic sarcoidosis with thyroid involvement
AU - Okuma, Hideyuki
AU - Hashimoto, Koshi
AU - Wang, Xin
AU - Ohkiba, Noriaki
AU - Murooka, Nozomi
AU - Akizuki, Norikazu
AU - Inazawa, Takeshi
AU - Ogawa, Yoshihiro
N1 - Publisher Copyright:
© 2017 The Japanese Society of Internal Medicine.
PY - 2017
Y1 - 2017
N2 - A 66-year-old woman, who was diagnosed with iritis, visited our hospital due to general malaise. A blood analysis revealed hypercalcemia. Computed tomography revealed mediastinal and hilar lymph node hyperpla-sia. Moreover,67Gallium scintigraphy demonstrated strong accumulation in the lesions, suggesting sarcoidosis. A core needle biopsy (CNB) of the hypoechoic areas of the thyroid was performed because the patient refused to undergo a bronchoscopic examination. The scattering of slightly acidophilic epithelioid cell granulo-mas was observed in the pathological examination of the biopsy specimen. Based on this finding, the patient was diagnosed with sarcoidosis. Although sarcoidosis rarely involves the thyroid gland, in the present case, thyroid CNB was an alternative diagnostic method that allowed a pathological diagnosis to be obtained.
AB - A 66-year-old woman, who was diagnosed with iritis, visited our hospital due to general malaise. A blood analysis revealed hypercalcemia. Computed tomography revealed mediastinal and hilar lymph node hyperpla-sia. Moreover,67Gallium scintigraphy demonstrated strong accumulation in the lesions, suggesting sarcoidosis. A core needle biopsy (CNB) of the hypoechoic areas of the thyroid was performed because the patient refused to undergo a bronchoscopic examination. The scattering of slightly acidophilic epithelioid cell granulo-mas was observed in the pathological examination of the biopsy specimen. Based on this finding, the patient was diagnosed with sarcoidosis. Although sarcoidosis rarely involves the thyroid gland, in the present case, thyroid CNB was an alternative diagnostic method that allowed a pathological diagnosis to be obtained.
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U2 - 10.2169/internalmedicine.8324-16
DO - 10.2169/internalmedicine.8324-16
M3 - Article
C2 - 28781308
AN - SCOPUS:85027573597
VL - 56
SP - 2181
EP - 2186
JO - Internal Medicine
JF - Internal Medicine
SN - 0918-2918
IS - 16
ER -