Systemic sarcoidosis with thyroid involvement

Hideyuki Okuma, Koshi Hashimoto, Xin Wang, Noriaki Ohkiba, Nozomi Murooka, Norikazu Akizuki, Takeshi Inazawa, Yoshihiro Ogawa

Research output: Contribution to journalArticle

Abstract

A 66-year-old woman, who was diagnosed with iritis, visited our hospital due to general malaise. A blood analysis revealed hypercalcemia. Computed tomography revealed mediastinal and hilar lymph node hyperpla-sia. Moreover,67Gallium scintigraphy demonstrated strong accumulation in the lesions, suggesting sarcoidosis. A core needle biopsy (CNB) of the hypoechoic areas of the thyroid was performed because the patient refused to undergo a bronchoscopic examination. The scattering of slightly acidophilic epithelioid cell granulo-mas was observed in the pathological examination of the biopsy specimen. Based on this finding, the patient was diagnosed with sarcoidosis. Although sarcoidosis rarely involves the thyroid gland, in the present case, thyroid CNB was an alternative diagnostic method that allowed a pathological diagnosis to be obtained.

Original languageEnglish
Pages (from-to)2181-2186
Number of pages6
JournalInternal Medicine
Volume56
Issue number16
DOIs
Publication statusPublished - 2017

All Science Journal Classification (ASJC) codes

  • Internal Medicine

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    Okuma, H., Hashimoto, K., Wang, X., Ohkiba, N., Murooka, N., Akizuki, N., Inazawa, T., & Ogawa, Y. (2017). Systemic sarcoidosis with thyroid involvement. Internal Medicine, 56(16), 2181-2186. https://doi.org/10.2169/internalmedicine.8324-16