Systemic sarcoidosis with thyroid involvement

Hideyuki Okuma; Koshi Hashimoto; Xin Wang; Noriaki Ohkiba; Nozomi Murooka; Norikazu Akizuki; Takeshi Inazawa; Yoshihiro Ogawa

doi:10.2169/internalmedicine.8324-16

Systemic sarcoidosis with thyroid involvement

Hideyuki Okuma, Koshi Hashimoto, Xin Wang, Noriaki Ohkiba, Nozomi Murooka, Norikazu Akizuki, Takeshi Inazawa, Yoshihiro Ogawa

Internal Medicine

Research output: Contribution to journal › Article

Abstract

A 66-year-old woman, who was diagnosed with iritis, visited our hospital due to general malaise. A blood analysis revealed hypercalcemia. Computed tomography revealed mediastinal and hilar lymph node hyperpla-sia. Moreover,⁶⁷Gallium scintigraphy demonstrated strong accumulation in the lesions, suggesting sarcoidosis. A core needle biopsy (CNB) of the hypoechoic areas of the thyroid was performed because the patient refused to undergo a bronchoscopic examination. The scattering of slightly acidophilic epithelioid cell granulo-mas was observed in the pathological examination of the biopsy specimen. Based on this finding, the patient was diagnosed with sarcoidosis. Although sarcoidosis rarely involves the thyroid gland, in the present case, thyroid CNB was an alternative diagnostic method that allowed a pathological diagnosis to be obtained.

Original language	English
Pages (from-to)	2181-2186
Number of pages	6
Journal	Internal Medicine
Volume	56
Issue number	16
DOIs	https://doi.org/10.2169/internalmedicine.8324-16
Publication status	Published - 2017

All Science Journal Classification (ASJC) codes

Internal Medicine

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Okuma, H., Hashimoto, K., Wang, X., Ohkiba, N., Murooka, N., Akizuki, N., Inazawa, T., & Ogawa, Y. (2017). Systemic sarcoidosis with thyroid involvement. Internal Medicine, 56(16), 2181-2186. https://doi.org/10.2169/internalmedicine.8324-16

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abstract = "A 66-year-old woman, who was diagnosed with iritis, visited our hospital due to general malaise. A blood analysis revealed hypercalcemia. Computed tomography revealed mediastinal and hilar lymph node hyperpla-sia. Moreover,67Gallium scintigraphy demonstrated strong accumulation in the lesions, suggesting sarcoidosis. A core needle biopsy (CNB) of the hypoechoic areas of the thyroid was performed because the patient refused to undergo a bronchoscopic examination. The scattering of slightly acidophilic epithelioid cell granulo-mas was observed in the pathological examination of the biopsy specimen. Based on this finding, the patient was diagnosed with sarcoidosis. Although sarcoidosis rarely involves the thyroid gland, in the present case, thyroid CNB was an alternative diagnostic method that allowed a pathological diagnosis to be obtained.",

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AU - Okuma, Hideyuki

AU - Hashimoto, Koshi

AU - Wang, Xin

AU - Ohkiba, Noriaki

AU - Murooka, Nozomi

AU - Akizuki, Norikazu

AU - Inazawa, Takeshi

AU - Ogawa, Yoshihiro

PY - 2017

Y1 - 2017

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