Analysis of the T-cell receptor has revealed the molecular basis of antigen recognition by T cells specific for viral antigens. Studies using T-cell receptor transgenic mice have provided evidence for clonal deletion of virus-specific T cells in persistently infected hosts and for selection of T-cell-resistant virus variants in vivo.
|Number of pages||5|
|Journal||Current Opinion in Immunology|
|Publication status||Published - Aug 1991|
All Science Journal Classification (ASJC) codes
- Immunology and Allergy