A chemical examination of the seed shells of Aesculus hippocastanum L. has led to the isolation of proanthocyanidins A-6 (10) and A-7 (11), and aesculitannins A (12), B (13), C (14), D (15), E (16), F (17) and G (18). On the basis of chemical and spectroscopic evidence, proanthocyanidins A-6 (10) and A-7 (11) have been determined to be A-type dimers each possessing a C-4, C-6 interflavanoid linkage, while aesculitannins A (12), B (13), C (14), D (15), E (16), F (17) and G (18) have been characterized as oligomeric proanthocyanidins possessing A-type unit(s) in each molecule. In addition, the presence of (— )-epicatechin (1), proanthocyanidins B-2 (2), B-5 (3), A-2 (4), A-4 (5) and C-l (6), epicatechin-(4β→6)-epicatechin-(4β→6)-epicatechin (7), and cinnamtannins B1(8) and B2 (9) was also demonstrated.
All Science Journal Classification (ASJC) codes
- Drug Discovery