Taste Sensing Systems Influencing Metabolic Consequences

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)

Abstract

Recent Findings: The taste information contributes to evaluate the quality and nutritional value of food before it is ingested, and thus, is essential for maintaining nutritive homeostasis within the body. Recent studies revealed that taste sensitivity is modulated by humoral factors such as hormones. Angiotensin II is a key hormone regulating sodium and water balance. Investigations of its involvement in the taste system revealed that angiotensin II suppresses the gustatory NaCl responses (amiloride-sensitive component) and enhances sweet taste sensitivity without affecting umami, sour, and bitter responses in mice. Summary: These results suggest that taste modulation by angiotensin II may play important roles in maintaining electrolyte and glucose homeostasis. Purpose of Review: This review focuses on the molecular mechanisms of salty taste perception and its modulation through the angiotensin II signaling to work out novel strategies to control food intake influencing metabolic consequences.

Original languageEnglish
Pages (from-to)79-86
Number of pages8
JournalCurrent Oral Health Reports
Volume4
Issue number2
DOIs
Publication statusPublished - Jun 2017

All Science Journal Classification (ASJC) codes

  • Immunology and Microbiology (miscellaneous)
  • Oral Surgery
  • Surgery

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