Abstract
We report here a novel chamber-sealing valve that is self-actuated by pressure change during the cyclic temperature changes in PCR processes. Actuation of our valve requirs only a heating device employed for PCR. An UV-curable polymer is used as a device material and it allowed us to realize temperature-driven valve actuation as well as to fabricate a 3D device. The self-actuated microvalve achieves the effective sealing of microchamber for PCR even at 90°C, which is essential to develop highly parallel PCR array device without any complicated actuator circuits.
| Original language | English |
|---|---|
| Title of host publication | 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 |
| Pages | 248-250 |
| Number of pages | 3 |
| Publication status | Published - Dec 1 2011 |
| Event | 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 - Seattle, WA, United States Duration: Oct 2 2011 → Oct 6 2011 |
Publication series
| Name | 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 |
|---|---|
| Volume | 1 |
Other
| Other | 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 |
|---|---|
| Country | United States |
| City | Seattle, WA |
| Period | 10/2/11 → 10/6/11 |
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All Science Journal Classification (ASJC) codes
- Control and Systems Engineering
Cite this
Temperature-driven self-actuated microvalve for PCR. / Naito, Toyohiro; Arayanarakool, Rerngchai; Kaji, Noritada; Okamoto, Yukihiro; Tokeshi, Manabu; Gac, Séverine Le; Van Den Berg, Albert; Baba, Y.
15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011. 2011. p. 248-250 (15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011; Vol. 1).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Temperature-driven self-actuated microvalve for PCR
AU - Naito, Toyohiro
AU - Arayanarakool, Rerngchai
AU - Kaji, Noritada
AU - Okamoto, Yukihiro
AU - Tokeshi, Manabu
AU - Gac, Séverine Le
AU - Van Den Berg, Albert
AU - Baba, Y.
PY - 2011/12/1
Y1 - 2011/12/1
N2 - We report here a novel chamber-sealing valve that is self-actuated by pressure change during the cyclic temperature changes in PCR processes. Actuation of our valve requirs only a heating device employed for PCR. An UV-curable polymer is used as a device material and it allowed us to realize temperature-driven valve actuation as well as to fabricate a 3D device. The self-actuated microvalve achieves the effective sealing of microchamber for PCR even at 90°C, which is essential to develop highly parallel PCR array device without any complicated actuator circuits.
AB - We report here a novel chamber-sealing valve that is self-actuated by pressure change during the cyclic temperature changes in PCR processes. Actuation of our valve requirs only a heating device employed for PCR. An UV-curable polymer is used as a device material and it allowed us to realize temperature-driven valve actuation as well as to fabricate a 3D device. The self-actuated microvalve achieves the effective sealing of microchamber for PCR even at 90°C, which is essential to develop highly parallel PCR array device without any complicated actuator circuits.
UR - http://www.scopus.com/inward/record.url?scp=84883748674&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84883748674&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:84883748674
SN - 9781618395955
T3 - 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
SP - 248
EP - 250
BT - 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
ER -