TY - GEN
T1 - Temperature-driven self-actuated microvalve for PCR
AU - Naito, Toyohiro
AU - Arayanarakool, Rerngchai
AU - Kaji, Noritada
AU - Okamoto, Yukihiro
AU - Tokeshi, Manabu
AU - Gac, Séverine Le
AU - Van Den Berg, Albert
AU - Baba, Y.
PY - 2011/12/1
Y1 - 2011/12/1
N2 - We report here a novel chamber-sealing valve that is self-actuated by pressure change during the cyclic temperature changes in PCR processes. Actuation of our valve requirs only a heating device employed for PCR. An UV-curable polymer is used as a device material and it allowed us to realize temperature-driven valve actuation as well as to fabricate a 3D device. The self-actuated microvalve achieves the effective sealing of microchamber for PCR even at 90°C, which is essential to develop highly parallel PCR array device without any complicated actuator circuits.
AB - We report here a novel chamber-sealing valve that is self-actuated by pressure change during the cyclic temperature changes in PCR processes. Actuation of our valve requirs only a heating device employed for PCR. An UV-curable polymer is used as a device material and it allowed us to realize temperature-driven valve actuation as well as to fabricate a 3D device. The self-actuated microvalve achieves the effective sealing of microchamber for PCR even at 90°C, which is essential to develop highly parallel PCR array device without any complicated actuator circuits.
UR - http://www.scopus.com/inward/record.url?scp=84883748674&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84883748674&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:84883748674
SN - 9781618395955
T3 - 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
SP - 248
EP - 250
BT - 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
T2 - 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
Y2 - 2 October 2011 through 6 October 2011
ER -