Temperature-responsive "catch and release" of proteins by using multifunctional polymer-based nanoparticles

Keiichi Yoshimatsu, Benjamin K. Lesel, Yusuke Yonamine, John M. Beierle, Yu Hoshino, Kenneth J. Shea

Research output: Contribution to journalArticlepeer-review

117 Citations (Scopus)

Abstract

Catch me if you can: Multifunctional, polymer-based nanoparticles that are capable of temperature-responsive "catch-and-release" of a target protein have been synthesized. The process is reversible and does not denature the proteins. An optimized combination of functional monomers imparts binding selectivity toward a target protein over other proteins.

Original languageEnglish
Pages (from-to)2405-2408
Number of pages4
JournalAngewandte Chemie - International Edition
Volume51
Issue number10
DOIs
Publication statusPublished - Mar 5 2012

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)

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