Temporary deterioration of pulmonary functions after injection sclerotherapy for cirrhotic patients with esophageal varices

S. Kitano, Y. Iso, H. Yamaga, M. Hashizume, H. Wada, K. Sugimachi

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

In 34 cirrhotic patients with esophageal varices, a significant but temporary deterioration in pulmonary function tests occurred 24 h after endoscopic injection sclerotherapy using 5% ethanolamine oleate. Included were vital capacity, forced expiratory volume in 1 s, closing volume/vital capacity and arterial oxygen content. Twenty-four hours after the sclerotherapy, the patients complaining of postinjection retrosternal pain had a larger fall in vital capacity and forced expiratory volume in 1 s than did the patients without pain. Before the injection sclerotherapy, 11 of 34 patients had an arterial hypoxemia (Pao, less than 80 mm Hg). In these patients, there was a significantly (p < 0.001) higher value of closing volume before sclerotherapy and there were larger changes in both closing volume (p <0.01) and arterial oxygen content (p < 0.01) 24 h after the injection sclerotherapy than in the patients without hypoxemia. Reversion to a state before sclerotherapy was attained 7 days after the sclerotherapy. Thus, patients undergoing sclerotherapy for bleeding esophageal varices should be closely monitored with regard to pulmonary function.

Original languageEnglish
Pages (from-to)298-303
Number of pages6
JournalEuropean Surgical Research
Volume20
Issue number5-6
DOIs
Publication statusPublished - Jan 1 1988

All Science Journal Classification (ASJC) codes

  • Surgery

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