The antiplatelet aggregation effects of aspirin suppositories

Hiroyuki Nakayasu; Masanobu Maeda; Takao Soda; Kenji Iijima; Manabu Ishimoto; Ichiro Ieiri; Fumie Tabuchi; Kenji Otsubo; Kenji Nakashima

doi:10.1159/000070112

The antiplatelet aggregation effects of aspirin suppositories

Hiroyuki Nakayasu, Masanobu Maeda, Takao Soda, Kenji Iijima, Manabu Ishimoto, Ichiro Ieiri, Fumie Tabuchi, Kenji Otsubo, Kenji Nakashima

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

To confirm that aspirin suppositories are an effective treatment for acute ischemic stroke, we examined the suppressive effects of 200-mg aspirin suppositories on platelet aggregation. Aspirin suppositories suppressed platelet aggregation induced by ADP or collagen, and the suppression continued for 24 h. There was no significant difference in suppression of platelet aggregation between aspirin administered by suppository and orally given aspirin. These results suggest that aspirin suppositories are a useful treatment for acute ischemic stroke.

Original language	English
Pages (from-to)	31-35
Number of pages	5
Journal	Cerebrovascular Diseases
Volume	16
Issue number	1
DOIs	https://doi.org/10.1159/000070112
Publication status	Published - 2003
Externally published	Yes

All Science Journal Classification (ASJC) codes

Neurology
Clinical Neurology
Cardiology and Cardiovascular Medicine

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10.1159/000070112

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AU - Maeda, Masanobu

AU - Soda, Takao

AU - Iijima, Kenji

AU - Ishimoto, Manabu

AU - Ieiri, Ichiro

AU - Tabuchi, Fumie

AU - Otsubo, Kenji

AU - Nakashima, Kenji

PY - 2003

Y1 - 2003

N2 - To confirm that aspirin suppositories are an effective treatment for acute ischemic stroke, we examined the suppressive effects of 200-mg aspirin suppositories on platelet aggregation. Aspirin suppositories suppressed platelet aggregation induced by ADP or collagen, and the suppression continued for 24 h. There was no significant difference in suppression of platelet aggregation between aspirin administered by suppository and orally given aspirin. These results suggest that aspirin suppositories are a useful treatment for acute ischemic stroke.

AB - To confirm that aspirin suppositories are an effective treatment for acute ischemic stroke, we examined the suppressive effects of 200-mg aspirin suppositories on platelet aggregation. Aspirin suppositories suppressed platelet aggregation induced by ADP or collagen, and the suppression continued for 24 h. There was no significant difference in suppression of platelet aggregation between aspirin administered by suppository and orally given aspirin. These results suggest that aspirin suppositories are a useful treatment for acute ischemic stroke.

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The antiplatelet aggregation effects of aspirin suppositories

Abstract

All Science Journal Classification (ASJC) codes

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