TY - JOUR
T1 - The calcium/NFAT pathway
T2 - role in development and function of regulatory T cells
AU - Oh-hora, Masatsugu
AU - rao, Anjana
N1 - Funding Information:
This work was supported by NIH and JDRF grants (to A.R.). M.O. was supported by a research fellowship from the Uehara Memorial Foundation.
Copyright:
Copyright 2009 Elsevier B.V., All rights reserved.
PY - 2009/4
Y1 - 2009/4
N2 - Calcium signals are essential for diverse cellular functions in the immune system. Sustained Ca2+ entry is necessary for complete and long-lasting activation of calcineurin/NFAT pathways. A growing number of studies have emphasized that Ca2+/calcineurin/NFAT pathway is crucial for both development and function of regulatory T cells.
AB - Calcium signals are essential for diverse cellular functions in the immune system. Sustained Ca2+ entry is necessary for complete and long-lasting activation of calcineurin/NFAT pathways. A growing number of studies have emphasized that Ca2+/calcineurin/NFAT pathway is crucial for both development and function of regulatory T cells.
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U2 - 10.1016/j.micinf.2009.04.008
DO - 10.1016/j.micinf.2009.04.008
M3 - Article
C2 - 19375514
AN - SCOPUS:67349260691
VL - 11
SP - 612
EP - 619
JO - Microbes and Infection
JF - Microbes and Infection
SN - 1286-4579
IS - 5
ER -