The calcium/NFAT pathway: role in development and function of regulatory T cells

Masatsugu Ohora, Anjana rao

    Research output: Contribution to journalArticle

    37 Citations (Scopus)

    Abstract

    Calcium signals are essential for diverse cellular functions in the immune system. Sustained Ca2+ entry is necessary for complete and long-lasting activation of calcineurin/NFAT pathways. A growing number of studies have emphasized that Ca2+/calcineurin/NFAT pathway is crucial for both development and function of regulatory T cells.

    Original languageEnglish
    Pages (from-to)612-619
    Number of pages8
    JournalMicrobes and Infection
    Volume11
    Issue number5
    DOIs
    Publication statusPublished - Apr 1 2009

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    Calcineurin
    Regulatory T-Lymphocytes
    Calcium
    Immune System

    All Science Journal Classification (ASJC) codes

    • Microbiology
    • Immunology
    • Infectious Diseases

    Cite this

    The calcium/NFAT pathway : role in development and function of regulatory T cells. / Ohora, Masatsugu; rao, Anjana.

    In: Microbes and Infection, Vol. 11, No. 5, 01.04.2009, p. 612-619.

    Research output: Contribution to journalArticle

    Ohora, Masatsugu ; rao, Anjana. / The calcium/NFAT pathway : role in development and function of regulatory T cells. In: Microbes and Infection. 2009 ; Vol. 11, No. 5. pp. 612-619.
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