The Distribution of Dioxin Concentrations in the Blood of Yusho Patients

Jumboku Kajiwara, Takashi Todaka, Hironori Hirakawa, Tsuguhide Hori, Teruaki Hirata, Takao Iida, Hiroshi Uchi, Masutaka Furue

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

In 1968, the contamination of cooking oil by heat-degraded polychlorinated biphenyls (PCBs) caused a case of mass poisoning, the so-called Yusho incident. The cause of Yusho disease is thought to be ingested toxic substances, including not only PCBs but also polychlorinated dibenzofuran (PCDFs) in Kanemi rice oil. We previously measured dioxins concentrations in the blood of 854 Yusho patients by annual medical examination from 2001 to 2013. We determined the concentrations of 2,3,4,7,8-PeCDF, 1,2,3,4,7,8-HxCDF, 1,2,3,6,7,8-HxCDF and 3,3',4,4',5,5'-HxCB (#169) in the blood of Yusho patients were more than double those of normal controls. In 2012, a new Yusho criteria was established. Family members living with a Yusho patient were also certified as Yusho patients and called Yusho family cohabitant patients. In this study, we compared the distribution of 2,3,4,7,8-PeCDF concentration in the blood of Yusho patients and Yusho family cohabitant patients. It was suspected that the distribution of 2,3,4,7,8-PeCDF concentration in Yusho family cohabitant patients would be lower than that of Yusho patients.

Original languageEnglish
Pages (from-to)149-153
Number of pages5
JournalFukuoka igaku zasshi = Hukuoka acta medica
Volume106
Issue number5
Publication statusPublished - May 1 2015

Fingerprint

Dioxins
Polychlorinated Biphenyls
Oils
Poisons
Cooking
Poisoning
Hot Temperature

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Kajiwara, J., Todaka, T., Hirakawa, H., Hori, T., Hirata, T., Iida, T., ... Furue, M. (2015). The Distribution of Dioxin Concentrations in the Blood of Yusho Patients. Fukuoka igaku zasshi = Hukuoka acta medica, 106(5), 149-153.

The Distribution of Dioxin Concentrations in the Blood of Yusho Patients. / Kajiwara, Jumboku; Todaka, Takashi; Hirakawa, Hironori; Hori, Tsuguhide; Hirata, Teruaki; Iida, Takao; Uchi, Hiroshi; Furue, Masutaka.

In: Fukuoka igaku zasshi = Hukuoka acta medica, Vol. 106, No. 5, 01.05.2015, p. 149-153.

Research output: Contribution to journalArticle

Kajiwara, J, Todaka, T, Hirakawa, H, Hori, T, Hirata, T, Iida, T, Uchi, H & Furue, M 2015, 'The Distribution of Dioxin Concentrations in the Blood of Yusho Patients', Fukuoka igaku zasshi = Hukuoka acta medica, vol. 106, no. 5, pp. 149-153.
Kajiwara J, Todaka T, Hirakawa H, Hori T, Hirata T, Iida T et al. The Distribution of Dioxin Concentrations in the Blood of Yusho Patients. Fukuoka igaku zasshi = Hukuoka acta medica. 2015 May 1;106(5):149-153.
Kajiwara, Jumboku ; Todaka, Takashi ; Hirakawa, Hironori ; Hori, Tsuguhide ; Hirata, Teruaki ; Iida, Takao ; Uchi, Hiroshi ; Furue, Masutaka. / The Distribution of Dioxin Concentrations in the Blood of Yusho Patients. In: Fukuoka igaku zasshi = Hukuoka acta medica. 2015 ; Vol. 106, No. 5. pp. 149-153.
@article{a6112b7c548e4bf6958f48d48764efd2,
title = "The Distribution of Dioxin Concentrations in the Blood of Yusho Patients",
abstract = "In 1968, the contamination of cooking oil by heat-degraded polychlorinated biphenyls (PCBs) caused a case of mass poisoning, the so-called Yusho incident. The cause of Yusho disease is thought to be ingested toxic substances, including not only PCBs but also polychlorinated dibenzofuran (PCDFs) in Kanemi rice oil. We previously measured dioxins concentrations in the blood of 854 Yusho patients by annual medical examination from 2001 to 2013. We determined the concentrations of 2,3,4,7,8-PeCDF, 1,2,3,4,7,8-HxCDF, 1,2,3,6,7,8-HxCDF and 3,3',4,4',5,5'-HxCB (#169) in the blood of Yusho patients were more than double those of normal controls. In 2012, a new Yusho criteria was established. Family members living with a Yusho patient were also certified as Yusho patients and called Yusho family cohabitant patients. In this study, we compared the distribution of 2,3,4,7,8-PeCDF concentration in the blood of Yusho patients and Yusho family cohabitant patients. It was suspected that the distribution of 2,3,4,7,8-PeCDF concentration in Yusho family cohabitant patients would be lower than that of Yusho patients.",
author = "Jumboku Kajiwara and Takashi Todaka and Hironori Hirakawa and Tsuguhide Hori and Teruaki Hirata and Takao Iida and Hiroshi Uchi and Masutaka Furue",
year = "2015",
month = "5",
day = "1",
language = "English",
volume = "106",
pages = "149--153",
journal = "Fukuoka Acta Medica",
issn = "0016-254X",
publisher = "福岡医学会",
number = "5",

}

TY - JOUR

T1 - The Distribution of Dioxin Concentrations in the Blood of Yusho Patients

AU - Kajiwara, Jumboku

AU - Todaka, Takashi

AU - Hirakawa, Hironori

AU - Hori, Tsuguhide

AU - Hirata, Teruaki

AU - Iida, Takao

AU - Uchi, Hiroshi

AU - Furue, Masutaka

PY - 2015/5/1

Y1 - 2015/5/1

N2 - In 1968, the contamination of cooking oil by heat-degraded polychlorinated biphenyls (PCBs) caused a case of mass poisoning, the so-called Yusho incident. The cause of Yusho disease is thought to be ingested toxic substances, including not only PCBs but also polychlorinated dibenzofuran (PCDFs) in Kanemi rice oil. We previously measured dioxins concentrations in the blood of 854 Yusho patients by annual medical examination from 2001 to 2013. We determined the concentrations of 2,3,4,7,8-PeCDF, 1,2,3,4,7,8-HxCDF, 1,2,3,6,7,8-HxCDF and 3,3',4,4',5,5'-HxCB (#169) in the blood of Yusho patients were more than double those of normal controls. In 2012, a new Yusho criteria was established. Family members living with a Yusho patient were also certified as Yusho patients and called Yusho family cohabitant patients. In this study, we compared the distribution of 2,3,4,7,8-PeCDF concentration in the blood of Yusho patients and Yusho family cohabitant patients. It was suspected that the distribution of 2,3,4,7,8-PeCDF concentration in Yusho family cohabitant patients would be lower than that of Yusho patients.

AB - In 1968, the contamination of cooking oil by heat-degraded polychlorinated biphenyls (PCBs) caused a case of mass poisoning, the so-called Yusho incident. The cause of Yusho disease is thought to be ingested toxic substances, including not only PCBs but also polychlorinated dibenzofuran (PCDFs) in Kanemi rice oil. We previously measured dioxins concentrations in the blood of 854 Yusho patients by annual medical examination from 2001 to 2013. We determined the concentrations of 2,3,4,7,8-PeCDF, 1,2,3,4,7,8-HxCDF, 1,2,3,6,7,8-HxCDF and 3,3',4,4',5,5'-HxCB (#169) in the blood of Yusho patients were more than double those of normal controls. In 2012, a new Yusho criteria was established. Family members living with a Yusho patient were also certified as Yusho patients and called Yusho family cohabitant patients. In this study, we compared the distribution of 2,3,4,7,8-PeCDF concentration in the blood of Yusho patients and Yusho family cohabitant patients. It was suspected that the distribution of 2,3,4,7,8-PeCDF concentration in Yusho family cohabitant patients would be lower than that of Yusho patients.

UR - http://www.scopus.com/inward/record.url?scp=84940973350&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84940973350&partnerID=8YFLogxK

M3 - Article

C2 - 26226677

AN - SCOPUS:84940973350

VL - 106

SP - 149

EP - 153

JO - Fukuoka Acta Medica

JF - Fukuoka Acta Medica

SN - 0016-254X

IS - 5

ER -