The effect of carbon dioxide pneumoperitoneum on the portal hemodynamics in a portal-hypertensive rat model

Kouji Tsugawa, Makoto Hashizume, Shinichirou Migou, Kazuo Tanoue, Fumiaki Kishihara, Hirofumi Kawanaka, Keizo Sugimachi

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

As use of laparoscopic surgery grows, various complications with pneumoperitoneum have been reported. However, there are no reports on the relation between the carbon dioxide (CO'2) pneumoperitoneum and portal hemodynamics. The purpose of this study was to determine how the pneumoperitoneum affects the portal hypertensive state. Portal-hypertensive rats, control rats, and sham operation rats were studied. The mean arterial pressure, portal venous pressure, central venous pressure, red blood flow volume of the viscera, and liver and renal function were investigated. The findings of this study suggest that CO'2 pneumoperitoneum at less than 10 mm Hg does not present any undue risk to the portal hemodynamics in portal- hypertensive rats; however, more attention should be paid to the IAP in PHT patients undergoing surgery.

Original languageEnglish
Pages (from-to)338-347
Number of pages10
JournalSurgical Laparoscopy and Endoscopy
Volume9
Issue number5
DOIs
Publication statusPublished - Jan 1 1999

Fingerprint

Pneumoperitoneum
Carbon Dioxide
Hemodynamics
Carbon Monoxide
Portal Pressure
Central Venous Pressure
Viscera
Blood Volume
Laparoscopy
Arterial Pressure
Kidney
Liver

All Science Journal Classification (ASJC) codes

  • Surgery

Cite this

The effect of carbon dioxide pneumoperitoneum on the portal hemodynamics in a portal-hypertensive rat model. / Tsugawa, Kouji; Hashizume, Makoto; Migou, Shinichirou; Tanoue, Kazuo; Kishihara, Fumiaki; Kawanaka, Hirofumi; Sugimachi, Keizo.

In: Surgical Laparoscopy and Endoscopy, Vol. 9, No. 5, 01.01.1999, p. 338-347.

Research output: Contribution to journalArticle

Tsugawa, K, Hashizume, M, Migou, S, Tanoue, K, Kishihara, F, Kawanaka, H & Sugimachi, K 1999, 'The effect of carbon dioxide pneumoperitoneum on the portal hemodynamics in a portal-hypertensive rat model', Surgical Laparoscopy and Endoscopy, vol. 9, no. 5, pp. 338-347. https://doi.org/10.1097/00129689-199910000-00005
Tsugawa, Kouji ; Hashizume, Makoto ; Migou, Shinichirou ; Tanoue, Kazuo ; Kishihara, Fumiaki ; Kawanaka, Hirofumi ; Sugimachi, Keizo. / The effect of carbon dioxide pneumoperitoneum on the portal hemodynamics in a portal-hypertensive rat model. In: Surgical Laparoscopy and Endoscopy. 1999 ; Vol. 9, No. 5. pp. 338-347.
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