The effect of endurance training on the relationships between sex hormone binding globulin, high density lipoprotein cholesterol, apoprotein A1 and physical fitness in pre-menopausal women with mild obesity

Shuzo Kumagai, N. Shono, Y. Kondo, M. Nishizumi

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Abstract

The purpose of the present study was to investigate the relationships of change in high density lipoprotein cholesterol (HDL-C) with changes in sex hormone binding globulin (SHBG), physical fitness and spontaneous dietary intake before and after endurance training. Ten pre-menopausal obese women (32 to 49 years) who had never smoked or regularly drunk alcohol participated in this study. Physical training at an intensity of lactate threshold was performed for six months at a frequency of three times per week for 60 minutes using a cycle ergometer. Together with a reduction in body weight (-4.1 kg; P < 0.05) and with increases in maximal oxygen uptake (V̇O 2 max = +3.4 ml/ kg/min or +0.09l/min; P < 0.05), the training induced some changes in both plasma lipid and lipoprotein. Although the total cholesterol (total-C), triglyceride, HDL 2 -C and apoprotein A1 (Apo A1) levels did not change, significant increases in HDL-C and HDL 3 -C, and significant reductions in Apo B, total-C/HDL-C ratio and fasting insulin concentrations were found after training. SHBG levels tended to increase after endurance training, but the changes were not significant. No alteration was observed in spontaneous dietary intake after training. A significant correlation (r = 0.648) was observed between the change in V̇O 2 max(l/min) and the change in SHBG. In addition, changes in both V̇O 2 max(l/min) and SHBG were significantly associated with changes in HDL-C, HDL 2 -C and Apo A1. The changes in dietary intake did not correlate with the changes in SHBG, V̇O 2 max, HDL-C, HDL 2 -C and Apo A1. From these results, it is suggested that the alteration of HDL-C metabolism after endurance training may be partially related to training-induced alterations of both aerobic work capacity and the SHBG level.

Original languageEnglish
Pages (from-to)249-254
Number of pages6
JournalInternational Journal of Obesity
Volume18
Issue number4
Publication statusPublished - Jan 1 1994

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Sex Hormone-Binding Globulin
Apoproteins
Physical Fitness
HDL Cholesterol
Obesity
Apolipoproteins C
HDL3 Lipoprotein
HDL2 Lipoprotein
Apolipoproteins B
Lipoproteins
Lactic Acid
Fasting
Triglycerides
Cholesterol
Body Weight
Alcohols
Insulin
Oxygen
Lipids

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Endocrinology, Diabetes and Metabolism
  • Nutrition and Dietetics

Cite this

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title = "The effect of endurance training on the relationships between sex hormone binding globulin, high density lipoprotein cholesterol, apoprotein A1 and physical fitness in pre-menopausal women with mild obesity",
abstract = "The purpose of the present study was to investigate the relationships of change in high density lipoprotein cholesterol (HDL-C) with changes in sex hormone binding globulin (SHBG), physical fitness and spontaneous dietary intake before and after endurance training. Ten pre-menopausal obese women (32 to 49 years) who had never smoked or regularly drunk alcohol participated in this study. Physical training at an intensity of lactate threshold was performed for six months at a frequency of three times per week for 60 minutes using a cycle ergometer. Together with a reduction in body weight (-4.1 kg; P < 0.05) and with increases in maximal oxygen uptake (V̇O 2 max = +3.4 ml/ kg/min or +0.09l/min; P < 0.05), the training induced some changes in both plasma lipid and lipoprotein. Although the total cholesterol (total-C), triglyceride, HDL 2 -C and apoprotein A1 (Apo A1) levels did not change, significant increases in HDL-C and HDL 3 -C, and significant reductions in Apo B, total-C/HDL-C ratio and fasting insulin concentrations were found after training. SHBG levels tended to increase after endurance training, but the changes were not significant. No alteration was observed in spontaneous dietary intake after training. A significant correlation (r = 0.648) was observed between the change in V̇O 2 max(l/min) and the change in SHBG. In addition, changes in both V̇O 2 max(l/min) and SHBG were significantly associated with changes in HDL-C, HDL 2 -C and Apo A1. The changes in dietary intake did not correlate with the changes in SHBG, V̇O 2 max, HDL-C, HDL 2 -C and Apo A1. From these results, it is suggested that the alteration of HDL-C metabolism after endurance training may be partially related to training-induced alterations of both aerobic work capacity and the SHBG level.",
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T1 - The effect of endurance training on the relationships between sex hormone binding globulin, high density lipoprotein cholesterol, apoprotein A1 and physical fitness in pre-menopausal women with mild obesity

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AU - Kondo, Y.

AU - Nishizumi, M.

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N2 - The purpose of the present study was to investigate the relationships of change in high density lipoprotein cholesterol (HDL-C) with changes in sex hormone binding globulin (SHBG), physical fitness and spontaneous dietary intake before and after endurance training. Ten pre-menopausal obese women (32 to 49 years) who had never smoked or regularly drunk alcohol participated in this study. Physical training at an intensity of lactate threshold was performed for six months at a frequency of three times per week for 60 minutes using a cycle ergometer. Together with a reduction in body weight (-4.1 kg; P < 0.05) and with increases in maximal oxygen uptake (V̇O 2 max = +3.4 ml/ kg/min or +0.09l/min; P < 0.05), the training induced some changes in both plasma lipid and lipoprotein. Although the total cholesterol (total-C), triglyceride, HDL 2 -C and apoprotein A1 (Apo A1) levels did not change, significant increases in HDL-C and HDL 3 -C, and significant reductions in Apo B, total-C/HDL-C ratio and fasting insulin concentrations were found after training. SHBG levels tended to increase after endurance training, but the changes were not significant. No alteration was observed in spontaneous dietary intake after training. A significant correlation (r = 0.648) was observed between the change in V̇O 2 max(l/min) and the change in SHBG. In addition, changes in both V̇O 2 max(l/min) and SHBG were significantly associated with changes in HDL-C, HDL 2 -C and Apo A1. The changes in dietary intake did not correlate with the changes in SHBG, V̇O 2 max, HDL-C, HDL 2 -C and Apo A1. From these results, it is suggested that the alteration of HDL-C metabolism after endurance training may be partially related to training-induced alterations of both aerobic work capacity and the SHBG level.

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