The effect of partial removal of troponin I and C on the Ca2+-sensitive ATPase activity of rabbit skeletal myofibrils1

Fumie Shiraishi, Kazuhiko Yamamoto

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The effect of partial removal of troponin I and C on the profiles of Ca2+-sensitive ATPase activity in rabbit skeletal myofibrils was investigated by replacing the troponin C.I. T-complex in the myofibrils with exogenously added troponin T under the same conditions as those reported previously [Shiraishi et al. (1992) J. Biochem. 111, 61-65]. During the course of the troponin T treatment, the level of the ATP hydrolysis at low Ca2+concentrations was elevated and the pCa for half maximum activation increased, while the cooperativity decreased. These changes in the parameters of the ATPase were correlated with the extent of the troponin I removal from myofibrils.

Original languageEnglish
Pages (from-to)171-173
Number of pages3
JournalJournal of biochemistry
Volume115
Issue number1
DOIs
Publication statusPublished - Jan 1994

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology

Fingerprint Dive into the research topics of 'The effect of partial removal of troponin I and C on the Ca<sup>2+</sup>-sensitive ATPase activity of rabbit skeletal myofibrils<sup>1</sup>'. Together they form a unique fingerprint.

Cite this