The effect of partial removal of troponin I and C on the Ca2+-sensitive ATPase activity of rabbit skeletal myofibrils1

Fumie Shiraishi, Kazuhiko Yamamoto

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    5 Citations (Scopus)

    Abstract

    The effect of partial removal of troponin I and C on the profiles of Ca2+-sensitive ATPase activity in rabbit skeletal myofibrils was investigated by replacing the troponin C.I. T-complex in the myofibrils with exogenously added troponin T under the same conditions as those reported previously [Shiraishi et al. (1992) J. Biochem. 111, 61-65]. During the course of the troponin T treatment, the level of the ATP hydrolysis at low Ca2+concentrations was elevated and the pCa for half maximum activation increased, while the cooperativity decreased. These changes in the parameters of the ATPase were correlated with the extent of the troponin I removal from myofibrils.

    Original languageEnglish
    Pages (from-to)171-173
    Number of pages3
    JournalJournal of biochemistry
    Volume115
    Issue number1
    DOIs
    Publication statusPublished - Jan 1994

    All Science Journal Classification (ASJC) codes

    • Biochemistry
    • Molecular Biology

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